Gout

Causes, Symptoms, and Treatment Remedies




Gout Treatment Remedies

 

The contents of this app are provided for educational purposes only and are not intended to diagnose, treat, cure, or prevent any disease or health condition. The information provided should not be considered as a substitute for the advice of a medical doctor or other healthcare professional.

What is Gout?

Uric acid normally dissolves in your blood and passes through the kidneys in the urine,

When the body produces too much uric acid or the kidneys excrete too little uric acid, uric acid can accumulate.

When uric acid accumulates, sharp needle-like urate crystals may form in a joint or surrounding tissue.

When sharp urate crystals form in joints or tissues they cause inflammation and pain.

Untreated gout may lead to the formation of deposits of urate crystals under the skin.

Gout Causes

You are more likely to develop gout if you have high levels of uric acid in your body.

Certain diseases and conditions contribute to the development of gout.

Certain medications can increase uric acid levels and lead to gout attacks.

Thiazide diuretics, commonly used to treat high blood pressure, increase uric acid levels.

Low-dose aspirin increases uric acid levels.

Anti-rejection drugs, given to people who have undergone an organ transplant, increase uric acid levels.

Diabetes makes a person more likely to develop gout.

Men are more likely to develop gout than women because men tend have higher levels of uric acid in their bloodstream.

Gout Symptoms

Gout pain is most severe within the first 12 to 24 hours after it begins.

There is usually a lingering discomfort in the affected joints following a gout episode.

When gout recurs after the initial attack, gout attacks last longer and affect more joints.

Gout that is left untreated can lead to worsening pain and joint damage.

Women are more likely to experience the signs and symptoms of gout after menopause.

People with untreated gout may have deposits of urate crystals under the skin that form nodules.

The nodules that form when urate crystals deposit under the skin are called tophi.

Gout tophi can develop on the fingers, hands, feet, elbows, or the back of the ankle.

Tophi are not usually painful, but they can become swollen and tender during gout attacks.

Urate crystals may collect in the urinary tract of people with gout, causing kidney stones with the potential for painful attacks if kidney stones enter the ureters.

Gout Diagnosis

Diagnosis of gout is often based on the clinical picture--the location and quality of the joint pain.

A joint fluid test may be used to establish a definite diagnosis of gout.

During a joint fluid test, the doctor uses a needle to draw fluid from the affected joint.

The fluid from a joint fluid test is examined under a microscope, to look for the presence of urate crystals.

If gout is suspected, your doctor may order a test to measure the level of uric acid in your blood.

Some people have high uric acid levels and never experience gout, while other people have normal levels of uric acid but do have signs and symptoms of gout.

It is important to exclude other disease that may present a clinical picture similar to gout.

The most important differential diagnosis in gout is septic arthritis.

Septic arthritis should be considered in people with gout pain who also have signs of infection or do not improve with treatment.

To differentiate septic arthritis from classic gout, joint fluid may be examined and cultured to detect the presence of bacteria.

Rheumatoid arthritis may present with symptoms similar to gout.

Sometimes the tophi associated with gout can be mistaken for basal cell carcinoma (a type of skin cancer) or other neoplasms.

Gout Treatment

Treatment for gout usually involves medications.

Your doctor may prescribe a higher dose of an NSAID to stop an acute attack, followed by a lower daily dose to prevent future attacks.

Doctors may prescribe colchicine for people with gout who are unable to take NSAIDs.

Colchicine reduces gout pain especially when started soon after symptoms appear.

Colchicine, a drug often used to treat gout, often has intolerable side effects such as nausea, vomiting and diarrhea.

Corticosteroid medications, such as prednisone, may control gout inflammation and pain.

Corticosteroids can be administered orally or injected directly to the joint affected by gout.

Corticosteroids are prescribed for people who are unable to take either NSAIDs or colchicine to treat their gout symptoms.

Because corticosteroids have side effects such as poor wound healing and suppressed immunity, they are prescribed at the lowest dose that will control gout symptoms and only used for a short time.

Gout Prevention

People who have several gout attacks a year may take medications to reduce the risk of gout-related complications.

Medications that block uric acid production are used to prevent gout attacks.

Xanthine oxidase inhibitors, including allopurinal and febuxostat, are used to prevent gout attacks because they limit the amount of uric acid your body makes.

Xanthine oxidase inhibitors may trigger a new, acute attack of gout if they are taken before a recent attack has completely resolved.

Taking a short dose of low-dose colchicine before starting a xanthine oxidase reduces the chance of triggering an acute gout attack.

Medications that improve uric acid removal can help prevent gout attacks.

Probenecid is sometimes used to prevent gout because it improves the kidney's ability to remove uric acid from the body.

While medications like probenecid lower the blood levels of uric acid, the level of uric acid in the urine is increased, so kidney stones can be a side effect of this gout medication.

After an acute gout attack, your doctor may prescribe a low daily dose of colchicine to prevent future attacks.

A low daily dose of an NSAID may help prevent future gout attacks.

During symptom-free periods, changes in diet can help prevent future gout attacks.

Maintaining a high intake of fluid, about 2 to 4 liters per day, with at least half of that being pure water, can help prevent gout attacks.

People with gout should limit their consumption of sweet beverages, especially drinks sweetened with high fructose corn syrup.

People with gout should limit or avoid alcohol consumption to reduce the chance of future attacks.

A balanced diet with plenty of fresh fruits, vegetables, whole grains and fat-free or low-fat milk products can help prevent future gout attacks.

Low-fat dairy products are the best protein sources for people with gout, because they may actually have a protective effect .

Certain meats, fish and poultry can increase uric acid levels, so people with gout should limit their intake of foods that seem to cause problems for them.

Losing weight may decrease uric acid levels in the body, helping prevent future gout attacks.

Fasting or rapid weight loss can temporarily raise uric acid levels, so people with gout should lose weight more gradually.

Vitamin C intake of 1,500 mg per day decreases the risk of gout by 45%.

Treatment of sleep apnea can decrease the frequency of recurrent attacks of gout; sleep apnea can increase uric acid levels due to the release of purines from oxygen-starved cells.

Gout Statistics & Facts

Recent evidence suggests that beer may be particularly likely to increase the risk of gout symptoms, especially in men.

Coffee consumption is associated with a lower risk of gout.

60% of people who have an acute gout attack will have a second attack within one year.

Formation of gout tophi occurs in 30% of people with gout who are left untreated for 5 years.

Kidney stones affect between 10 and 40% of people with gout.

Gout affects around 1-2% of the Western population at some point in their lifetimes and is becoming more common.

In the US, gout is twice as likely in African American males as it is in European Americans.

Gout is becoming more common in China, Polynesia and urban sub-Saharan Africa.

Some studies suggest that attacks of gout occur more frequently in the spring, perhaps due to seasonal changes in diet, temperature and alcohol consumption.

Gout has historically been referred to as "the kind of diseases and the disease of kings," or "rich man's disease."

Gout is rare in most other animals due to their ability to produce uricase, which breaks down uric acid.

Gout was first documented as a disorder in 2,600BC in a description of arthritis of the big toe.

The increase in the incidence of gout is believed to be due to factors such as longer life expectancy and changes in diet.

The base of the big toe is affected most often, accounting for 50% of all cases of gout.

The reason for onset of gout attacks at night is due to lower body temperature during sleep.

Underexcretion of uric acid by the kidney is the primary cause of hyperuricemia in about 90% of cases of gout, while overproduction of uric acid by the body is the cause in less than 10% of cases.

Three genes have been found to be commonly associated with gout, and variations in them can approximately double the risk.

Mutations in certain genes can cause hereditary hypouricemia by reducing the reabsorption of urate in the kidney (which increases levels of urate in the blood).



Gout Treatment Remedies plus




The contents of this app are provided for educational purposes only and are not intended to diagnose, treat, cure, or prevent any disease or health condition. The information provided should not be considered as a substitute for the advice of a medical doctor or other healthcare professional.

What is Gout?

Gout occurs when urate crystals accumulate in a joint.

Accumulation of urate crystals causes the inflammation in the joint that leads to gout pain.

Urate crystals can form when you have high levels of uric acid in your bloodstream.

The body produces uric acid when it breaks down substances called purines that are found naturally in the body and in certain foods.

Foods that contain uric acid include organ meats, anchovies, herring, asparagus and mushrooms.

Gout Causes

Excessive alcohol consumption increases the uric acid level in your body and can contribute to the development of gout.

Untreated high blood pressure may contribute tot the development of gout.

High levels of fat and cholesterol in the blood (hyperlipidemia) and narrowing of the arteries (atherosclerosis) make people more likely to develop gout.

There may be a genetic component to the development of gout, because you are more likely to have gout if someone else in your family has it.

The rate of gout in women increases after menopause because of rising uric acid levels.

Gout Symptoms

The primary symptom of gout is intense joint pain.

Gout pain can occur in the joints of the feet, ankles, knees, hands and wrists.

Gout usually affects the joint of the big toe.

The signs and symptoms of gout almost always occur suddenly, at night, and without warning.

Joint discomfort may last from a few days to a few weeks following an attack of gout.

Gout Treatment

Gout medications can be used to treat acute attacks and prevent further attacks.

Gout medications can reduce the risk of complications from gout, such as the development of tophi from urate crystal deposits.

Nonsteroidal anti-inflammatory drugs (NSAIDS) may help control inflammation and pain in people with gout.

NSAIDS used to treat gout include the over the counter options, such as ibuprofen and naproxen, as well as more powerful prescription NSIADs such as indomethacin.

NSAIDs carry the risk of stomach pain, bleeding and ulcers, so some people with gout may not be able to tolerate NSAIDs.



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